The two become lovers and set out on a mission to expose the media and the medical establishment for their negligent response to the epidemic. The Busby Berkeley-style musical numbers include such unforgettable numbers as 'The Butthole Duet.'
This is an extremely strange musical recounting the AIDS crisis. Parts of it are very well done; though I think I can live the rest of my life without ever seeing two assholes (literally) singing.
The human, Burton, is putting together an exhibit on the origins of AIDS for the 'Hall of Contagions.' The subject of his project is Patient Zero, the supposed carrier of AIDS from Africa to North America. Burton's initial motives are mercenary, but encounters with Patient Zero's ghost changes his views on quite a number of things, including his own sexuality, as he falls in love with the ghost.